SOFT TISSUE WOUND HEALING REVIEW
Introduction
The inflammatory and repair processes are no longer simple events to
describe in light of the increased knowledge in this field. The review that
follows is only a brief resume of the salient events associated with tissue
repair, particularly concerning the soft tissues. For further information, the
reader is referred to recent reviews listed at the end of the paper.
Wound
healing refers to the body’s replacement of destroyed tissue by living tissue
and comprises two essential components – Regeneration and Repair. The
differentiation between the two is based on the resultant tissue. In
regeneration, specialized tissues are replaced by the proliferation of
surrounding undamaged specialized cells. In repair, lost tissue is replaced by
granulation tissue which matures to form scar tissue. This review concentrates
on the events and processes associated with the repair process.
Probably
the most straightforward way to describe the healing process is to divide it up
into broad stages which are not mutually exclusive and overlap considerably.
There are several different ways to “divide up” the entire process, but the
allocation of 4 phases is common and will be adopted here – these being
Bleeding, Inflammation, Proliferation and Remodeling.
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